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Medications & Supplements

  • Prazosin is given by mouth and is used to reduce urinary sphincter tone to relax the bladder and allow easier urination in dogs and cats. It may also be used as a treatment for congestive heart failure, systemic hypertension, or pulmonary hypertension in dogs. Give as directed. Common side effects include lethargy, vomiting, diarrhea, nausea, and constipation. This medication should be used with caution in pets with kidney disease or other conditions that cause low blood pressure, as well as in MDR1-positive dogs. If a negative reaction occurs, contact your veterinarian.

  • Prednisolone ophthalmic is a topical steroid medication used to treat inflammatory eye conditions in cats, dogs, and other animals. Prednisolone ophthalmic is available as a sole agent or in combination with antimicrobials. It may be used “off label” or “extra label” to treat other eye conditions. Prednisolone ophthalmic comes in ointment and liquid drop form. Avoid use in animals with viral or fungal infections, corneal ulceration, and birds.

  • Pregabalin (brand name Lyrica®), is an anticonvulsant and neuropathic pain medication. It is used to treat refractory or complex partial seizures and chronic neuropathic pain in small animals. It has been used to treat other types of pain in cats and dogs. It is used "off label" or "extra label" in animals. Pregabalin comes in capsule or liquid suspension form.

  • Ropinirole ophthalmic (Clevor®) is the first FDA-approved drug for inducing vomiting in dogs. Your veterinarian may prescribe this drug off label to use for your dog at home. Ropinirole ophthalmic comes as a single-use dropper for use in the eye.

  • SAMe or S-adenosyl-methionine + Silybin (brand name: Denamarin®) is a combination supplement commonly used to support liver health in cats and dogs. The body uses SAMe for many important functions, such as brain, heart, hormone, antioxidant, detoxifying, and other metabolic functions. The combination of SAMe and Silybin is used to support liver and brain health. This article discusses side effects, interactions, monitoring, and storage.

  • Salicylic acid topical (brand name Solva-Ker®, BioSeb®, Cerasoothe® SA, others) is an antimicrobial and antipruritic (anti-itching) agent used in the treatment of seborrheic (dry or greasy dandruff) disorders in cats, dogs, and other animals. It may be specially compounded and/or combined into a formulation with other medications. It comes in cream, gel, ointment, and shampoo forms.

  • Seboliance (brand name Douxo®S3 SEB) is a natural extract from the pomegranate plant (Punica granatum) used to help control dandruff, reduce odor, and help hydrate dry skin in cats and dogs. Seboliance may be part of a combination product containing ophytrium. Seboliance comes in mousse and shampoo forms.

  • Selamectin + sarolaner is used topically on the skin to treat various parasites, both on and off-label, and prevent heartworm in cats. Side effects are rare but may include hair loss at the application site, gastrointestinal upset, skin reactions, or neurologic signs. It should be used with caution in sick or underweight cats. If a negative reaction occurs, please call your veterinary office.

  • Ophthalmic autologous serum is a blood-derived product used to treat corneal ulcers in animals. Ophthalmic autologous serum is part of the blood and is collected directly from the patient. It is in liquid form.

  • Silver sulfadiazine topical is an antimicrobial used to treat skin infections and burns in cats, dogs, and exotic pets. It is used off label in veterinary medicine. Silver sulfadiazine topical comes in a topical cream.